Innovations in point-of-care electrochemical detection of pyocyanin

Pseudomonas Aeruginosa (P. Aeruginosa) is a prevalent and opportunistic bacterium which frequently causes severe nosocomial infection. Current clinical detection methods are limited in terms of necessary time equipment. Increasingly, P. Aeruginosa’s electrochemically active virulence factor pyocyanin has facilitated its rapid detection, primarily through voltammetric such as cyclic voltammetry (CV), differential pulse (DPV) square wave (SWV). A comprehensive background on the synthesis pathogenicity via (PyoC), included herein. Innovative electrochemical sensor design modification reviewed, with focus screen-printed electrodes, paper-based devices, arrays, surface biorecognition elements aptasensors.